Emergence of Escherichia coli producing OXA-48 β-lactamase in the community in Switzerland

Emergence of OXA-48-producing Enterobacteriaceae in Switzerland.

Emergence of OXA-48-producing Escherichia coli clone ST38 in France.

The blaOXA-48 gene encodes a carbapenem-hydrolyzing class D -lactamase that was first identified in Klebsiella pneumoniae from Turkey in 2003 and then extensively in that country (1, 11). There are few reports of blaOXA-48 in Escherichia coli, from Turkey, Israel, and Senegal (5, 6, 9). Furthermore, recent studies identified the spread of OXA-48-producers in North Africa (4, 12). E. coli NAA wa...

Emergence of OXA-48 carbapenemase-producing Escherichia coli and Klebsiella pneumoniae in dogs.

OBJECTIVES To evaluate the possible occurrence of carbapenemase-producing Escherichia coli and Klebsiella spp. strains in domestic animals. METHODS Veterinary clinical E. coli (n = 1175) and Klebsiella spp. (n = 136) isolates consecutively collected from livestock and companion animals in Germany from June 2012 to October 2012 were screened for their susceptibility to carbapenems using the ag...

Emergence of OXA-48-Producing Klebsiella pneumoniae in Taiwan

The isolation of OXA-48-producing Enterobacteriaceae has increased dramatically in Mediterranean countries in the past 10 years, and has recently emerged in Asia. Between January 2012 and May 2014, a total of 760 carbapenem non-susceptible Klebsiella pneumoniae (CnSKP) isolates were collected during a Taiwan national surveillance. Carbapenemases were detected in 210 CnSKP isolates (27.6%), incl...

Spread of Klebsiella pneumoniae isolates producing OXA-48 β-lactamase in a Tunisian university hospital.

Sir, The emergence and dissemination of Klebsiella pneumoniae isolates harbouring carbapenemases is a serious problem. Since the initial report of the OXA-48 enzyme in a K. pneumoniae isolate from Turkey in 2001, OXA-48 producers have been reported in many countries of the world. – 4 Current reports indicate that OXA-48 producers are widespread, mostly from Mediterranean countries as well as ot...